INDIANAPOLIS — Eli Manning and the Giants one-upped Tom Brady and the Patriots again, coming back with a last-minute score to beat New England 21-17 Sunday night for New York’s fourth Super Bowl title.

It was a rematch of the 2008 NFL championship, when Manning led New York past New England to ruin the Patriots’ bid for a perfect season.

Additional Photos

New York Giants wide receiver Victor Cruz makes a catch for a touchdown as New England Patriots safety James Ihedigbo defends during the first quarter of Super Bowl XLVI in Indianapolis. The Associated Press

New York Giants running back Ahmad Bradshaw backs into the end zone for the winning touchdown in front of New England Patriots linebacker Jerod Mayo in the final minute of Super Bowl XLVI. The Associated Press

New England Patriots running back Danny Woodhead scores a touchdown with 8 seconds left in the first half of Super Bowl XLVI on Sunday. The Associated Press

This was the first Super Bowl with two starting quarterbacks who previously won the big game’s MVP award — and they took turns being brilliant. Manning became the first QB to open a Super Bowl with nine consecutive completions. Later, Brady put together a run of 16 completions in a row, breaking another Super Bowl mark.

But in the end, it was Manning who directed the nine-play, 88-yard drive that put New York ahead.

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